9JKR

human GM-CSF with Fabs from autoantibodies, F1 and C.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fab region of F1 antibody heavy chain	polymer	231	24706.6	1		Homo sapiens
2	B (B)	Fab region of F1 antibody light chain	polymer	215	23494.3	1		Homo sapiens
3	C (C)	Fab region of C antibody heavy chain	polymer	236	25442.5	1		Homo sapiens
4	D (D)	Fab region of C antibody light chain	polymer	221	24459.3	1		Homo sapiens
5	E (I)	Granulocyte-macrophage colony-stimulating factor	polymer	149	17191.4	1	UniProt (P04141)	Homo sapiens (human)	GM-CSF,Colony-stimulating factor,CSF,Molgramostin,Sargramostim

Sequence modifications

I: 18 - 145 (UniProt: P04141)

PDB	External Database	Details
Gly 146	-	expression tag
Leu 147	-	expression tag
Asn 148	-	expression tag
Asp 149	-	expression tag
Ile 150	-	expression tag
Phe 151	-	expression tag
Glu 152	-	expression tag
Ala 153	-	expression tag
Gln 154	-	expression tag
Lys 155	-	expression tag
Ile 156	-	expression tag
Glu 157	-	expression tag
Trp 158	-	expression tag
His 159	-	expression tag
Glu 160	-	expression tag
Gly 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	115294.0
All*	Total formula weight	115294.0

*Water molecules are not included.