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9I0Z

Human protein kinase CK2 alpha in complex with TN11

This is a non-PDB format compatible entry.
Summary for 9I0Z
Entry DOI10.2210/pdb9i0z/pdb
Related8C6L 8C6M 8C6N
DescriptorCasein kinase II subunit alpha, SULFATE ION, (2~{Z},5~{Z})-5-[(4-methoxy-3-oxidanyl-phenyl)methylidene]-2-(2-methylphenyl)imino-1,3-thiazolidin-4-one, ... (5 entities in total)
Functional Keywordskinase domain, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight40152.60
Authors
Dalle Vedove, A.,Cazzanelli, G.,Lolli, G. (deposition date: 2025-01-15, release date: 2025-02-26)
Primary citationCazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Zasso, J.,Aiello, G.,Zonta, F.,Astolfi, A.,Barreca, M.L.,Ruzzene, M.,Tiberi, L.,Fava, L.L.,Quattrone, A.,Lolli, G.
Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.55 Å)
Structure validation

246704

PDB entries from 2025-12-24

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