9HVY

Cryo-EM structure of human separase-SCC1 (1-631) fusion protein

Summary for 9HVY

• Entry DOI: 10.2210/pdb9hvy/pdb
• EMDB information: 52288 52290 52445
• Descriptor: Double-strand-break repair protein rad21 homolog,Separin, ZINC ION (2 entities in total)
• Functional Keywords: separase, cell cycle, scc1, rad21, protease, chromosome segregation, auto-cleavage
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 311242.32

Authors

Yu, J.,Schmidt, S.,Botto, M.,Boland, A. (deposition date: 2025-01-02, release date: 2026-01-14)

• Primary citation: Yu, J.,Schmidt, S.,Botto, M.,Ghent, C.M.,Morgan, D.O.,Boland, A.; Structural insights into cohesin cleavage by human separase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)