9HVY
Cryo-EM structure of human separase-SCC1 (1-631) fusion protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Double-strand-break repair protein rad21 homolog,Separin | polymer | 2819 | 311176.9 | 1 | UniProt (O60216) UniProt (Q14674) | Homo sapiens (human) | hHR21,Nuclear matrix protein 1,NXP-1,SCC1 homolog,Caspase-like protein ESPL1,Extra spindle poles-like 1 protein,Separase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: -658 - -28 (UniProt: O60216)
A: 1 - 2120 (UniProt: Q14674)
| PDB | External Database | Details |
|---|---|---|
| Gly -27 | - | linker |
| Gly -26 | - | linker |
| Ser -25 | - | linker |
| Gly -24 | - | linker |
| Gly -23 | - | linker |
| Gly -22 | - | linker |
| Gly -21 | - | linker |
| Ser -20 | - | linker |
| Gly -19 | - | linker |
| Gly -18 | - | linker |
| Gly -17 | - | linker |
| Gly -16 | - | linker |
| Ser -15 | - | linker |
| Gly -14 | - | linker |
| Gly -13 | - | linker |
| Ser -12 | - | linker |
| Gly -11 | - | linker |
| Gly -10 | - | linker |
| Ser -9 | - | linker |
| Gly -8 | - | linker |
| Gly -7 | - | linker |
| Gly -6 | - | linker |
| Ser -5 | - | linker |
| Gly -4 | - | linker |
| Gly -3 | - | linker |
| Gly -2 | - | linker |
| Ser -1 | - | linker |
| Gly 0 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Asp 25 | Ala 25 | conflict |
| Val 116 | Ala 116 | conflict |
| Ser 1329 | Arg 1329 | conflict |
| Gln 1561 | Arg 1561 | conflict |
| Ser 2029 | Cys 2029 | conflict |
| His 2037 | Arg 2037 | conflict |
| Ser 2121 | - | expression tag |
| Ser 2122 | - | expression tag |
| Leu 2123 | - | expression tag |
| Ala 2124 | - | expression tag |
| Glu 2125 | - | expression tag |
| Glu 2126 | - | expression tag |
| Asn 2127 | - | expression tag |
| Leu 2128 | - | expression tag |
| Tyr 2129 | - | expression tag |
| Phe 2130 | - | expression tag |
| Gln 2131 | - | expression tag |
| Ser 2132 | - | expression tag |
| Trp 2133 | - | expression tag |
| Ser 2134 | - | expression tag |
| His 2135 | - | expression tag |
| Pro 2136 | - | expression tag |
| Gln 2137 | - | expression tag |
| Phe 2138 | - | expression tag |
| Glu 2139 | - | expression tag |
| Lys 2140 | - | expression tag |
| Gly 2141 | - | expression tag |
| Gly 2142 | - | expression tag |
| Gly 2143 | - | expression tag |
| Ser 2144 | - | expression tag |
| Gly 2145 | - | expression tag |
| Gly 2146 | - | expression tag |
| Gly 2147 | - | expression tag |
| Ser 2148 | - | expression tag |
| Gly 2149 | - | expression tag |
| Gly 2150 | - | expression tag |
| Gly 2151 | - | expression tag |
| Ser 2152 | - | expression tag |
| Trp 2153 | - | expression tag |
| Ser 2154 | - | expression tag |
| His 2155 | - | expression tag |
| Pro 2156 | - | expression tag |
| Gln 2157 | - | expression tag |
| Phe 2158 | - | expression tag |
| Glu 2159 | - | expression tag |
| Lys 2160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 311176.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 311242.3 |
