9HMI

Crystal structure of the Calf domains of Integrin Alpha5 in complex with angiopoietin2 peptide

Summary for 9HMI

• Entry DOI: 10.2210/pdb9hmi/pdb
• Related: 9HMH
• Descriptor: Integrin alpha-5, Angiopoietin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: integrin, alpha5-integrin, angiopoietin-2, angpt2, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 41479.63

Authors

Murthy, A.V.,Sipila, T.J.O.,Ponna, S.K.,Leppanen, V.M.L.,Saharinen, P.I. (deposition date: 2024-12-09, release date: 2026-05-20)

• Primary citation: Sipila, T.,Murthy, A.V.,Ponna, S.K.,Pink, A.,Enkavi, G.,Vattulainen, I.,Leppanen, V.M.,Saharinen, P.; Angiopoietin-2 interactions with active vs inactive alpha5beta1-integrin at cell-cell junctions determine TIE2-FOXO1 pathway activation; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.78 Å)