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9HMH

Crystal structure of the Calf domains of Integrin Alpha5

Summary for 9HMH
Entry DOI10.2210/pdb9hmh/pdb
DescriptorIntegrin alpha-5 (2 entities in total)
Functional Keywordsintegrin, alpha5-integrin, angiopoietin-2, angpt2, signaling protein
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight40251.33
Authors
Murthy, A.V.,Sipila, T.J.O.,Ponna, S.K.,Leppanen, V.M.L.,Saharinen, P.I. (deposition date: 2024-12-09, release date: 2026-05-20)
Primary citationSipila, T.,Murthy, A.V.,Ponna, S.K.,Pink, A.,Enkavi, G.,Vattulainen, I.,Leppanen, V.M.,Saharinen, P.
Angiopoietin-2 interactions with active vs inactive alpha5beta1-integrin at cell-cell junctions determine TIE2-FOXO1 pathway activation
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.92 Å)
Structure validation

254917

PDB entries from 2026-06-10

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