9HMH
Crystal structure of the Calf domains of Integrin Alpha5
Summary for 9HMH
| Entry DOI | 10.2210/pdb9hmh/pdb |
| Descriptor | Integrin alpha-5 (2 entities in total) |
| Functional Keywords | integrin, alpha5-integrin, angiopoietin-2, angpt2, signaling protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 40251.33 |
| Authors | Murthy, A.V.,Sipila, T.J.O.,Ponna, S.K.,Leppanen, V.M.L.,Saharinen, P.I. (deposition date: 2024-12-09, release date: 2026-05-20) |
| Primary citation | Sipila, T.,Murthy, A.V.,Ponna, S.K.,Pink, A.,Enkavi, G.,Vattulainen, I.,Leppanen, V.M.,Saharinen, P. Angiopoietin-2 interactions with active vs inactive alpha5beta1-integrin at cell-cell junctions determine TIE2-FOXO1 pathway activation To Be Published, |
| Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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