9HIW

Cryo-EM structure of CDK2-cyclin A bound to a SAMHD1 peptide

Summary for 9HIW

• Entry DOI: 10.2210/pdb9hiw/pdb
• Related: 9HIU
• EMDB information: 52201 52204
• Descriptor: Cyclin-A2, Cyclin-dependent kinase 2, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (3 entities in total)
• Functional Keywords: kinase, cyclin, short linear motif, cdk2, cyclin a, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 84012.68

Authors

de Martin Garrido, N.,Ord, M.,Cushing, V.I.,Greber, B.J.,Pryciak, P.M.,Davey, N.E. (deposition date: 2024-11-27, release date: 2025-08-20)

• Primary citation: Ord, M.,Winters, M.J.,Subbanna, M.,de Martin Garrido, N.,Cushing, V.I.,Kliche, J.,Benz, C.,Ivarsson, Y.,Greber, B.J.,Pryciak, P.M.,Davey, N.E.; Cryo-EM structure of CDK2-cyclin A bound to a SAMHD1 peptide; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)