9HIW
Cryo-EM structure of CDK2-cyclin A bound to a SAMHD1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-A2 | polymer | 432 | 48595.5 | 1 | UniProt (P20248) Pfam (PF16500) Pfam (PF00134) Pfam (PF02984) | Homo sapiens (human) | Cyclin-A,Cyclin A |
| 2 | B (B) | Cyclin-dependent kinase 2 | polymer | 297 | 33863.3 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | Cell division protein kinase 2,p33 protein kinase |
| 3 | C (C) | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | polymer | 13 | 1553.8 | 1 | UniProt (Q9Y3Z3) | Homo sapiens | dNTPase,Dendritic cell-derived IFNG-induced protein,DCIP,Monocyte protein 5,MOP-5,SAM domain and HD domain-containing protein 1,hSAMHD1 |
Sequence modifications
A: 1 - 432 (UniProt: P20248)
| PDB | External Database | Details |
|---|---|---|
| Val 163 | Ile 163 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 84012.7 | |
| All* | Total formula weight | 84012.7 |
