9GVU

Human Rab27A in complex with cyclic peptide IMP-2660

Summary for 9GVU

• Entry DOI: 10.2210/pdb9gvu/pdb
• Descriptor: Ras-related protein Rab-27A, Cyclic peptide IMP-2660, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: macrocyclic peptides, mrna display, rab27a, ppi inhibitor, exocytosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 47729.69

Authors

Petracca, R.,Tersa, M.,De Vita, E.,Morgan, M.R.,Cota, E.,Tate, E.W. (deposition date: 2024-09-25, release date: 2025-10-15)

• Primary citation: Petracca, R.,Tersa, M.,De Vita, E.,Morgan, M.R.,Cota, E.,Tate, E.W.; A potent macrocyclic peptide modulator of Rab27a identified by RaPID screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)