9GVU
Human Rab27A in complex with cyclic peptide IMP-2660
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ras-related protein Rab-27A | polymer | 184 | 20953.7 | 2 | UniProt (P51159) Pfam (PF00071) | Homo sapiens (human) | Rab-27,GTP-binding protein Ram |
| 2 | C, D (D, F) | Cyclic peptide IMP-2660 | polymer | 14 | 1720.0 | 2 | Synthetic construct | ||
| 3 | E, N (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, G, H, I, J... (A, B, D, F) | GLYCEROL | non-polymer | 92.1 | 14 | Chemie (GOL) | |||
| 5 | M, T (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 6 | W, X, Y, Z (A, B, D, F) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A, B: 5 - 188 (UniProt: P51159)
| PDB | External Database | Details |
|---|---|---|
| Leu 78 | Gln 78 | engineered mutation |
| Ser 123 | Cys 123 | engineered mutation |
| Ser 188 | Cys 188 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 45347.4 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2382.3 | |
| All* | Total formula weight | 47729.7 |
