9G35

The HIV protease inhibitor lopinavir binding to the active site of Cryphonectria parasitica endothiapepsin

9G35 の概要

• エントリーDOI: 10.2210/pdb9g35/pdb
• 関連するPDBエントリー: 9FVO 9G34
• 分子名称: Endothiapepsin, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, TRIETHYLENE GLYCOL, ... (6 entities in total)
• 機能のキーワード: aspartic protease, drug development, inhibitor, x-ray crystallographic screening, chestnut blight fungus, protease model, hydrolase
• 由来する生物種: Cryphonectria parasitica (chestnut blight fungus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35105.42

構造登録者

Falke, S.,Senst, J.M.,Guenther, S.,Meents, A. (登録日: 2024-07-11, 公開日: 2024-07-24, 最終更新日: 2024-11-13)

• 主引用文献: Falke, S.,Senst, J.M.,Guenther, S.,Meents, A.; The HIV protease inhibitor lopinavir binding to the active site of Cryphonectria parasitica endothiapepsin; To Be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)