9FVO

The HIV protease inhibitor amprenavir binding to the active site of Cryphonectria parasitica endothiapepsin

Summary for 9FVO

• Entry DOI: 10.2210/pdb9fvo/pdb
• Descriptor: Endothiapepsin, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• Functional Keywords: aspartic protease, drug development, inhibitor, x-ray crystallographic screening, chestnut blight fungus, protease model., hydrolase
• Biological source: Cryphonectria parasitica (chestnut blight fungus)
• Total number of polymer chains: 1
• Total formula weight: 35508.81

Authors

Falke, S.,Senst, J.M.,Guenther, S.,Meents, A. (deposition date: 2024-06-27, release date: 2024-07-10, Last modification date: 2024-10-23)

• Primary citation: Falke, S.,Senst, J.M.,Guenther, S.,Meents, A.; The HIV protease inhibitor amprenavir binding to the active site of Cryphonectria parasitica endothiapepsin; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)