9G35
The HIV protease inhibitor lopinavir binding to the active site of Cryphonectria parasitica endothiapepsin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endothiapepsin | polymer | 330 | 33813.9 | 1 | UniProt (P11838) Pfam (PF00026) | Cryphonectria parasitica (chestnut blight fungus) | Aspartate protease |
| 2 | B (A) | N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE | non-polymer | 628.8 | 1 | Chemie (AB1) | |||
| 3 | C (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 4 | D, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | E, G (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 6 | H (A) | water | water | 18.0 | 387 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33813.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1291.6 | |
| All* | Total formula weight | 35105.4 |
