9FG9

Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Etomidate in the long-lived symmetric desensitised state

Summary for 9FG9

• Entry DOI: 10.2210/pdb9fg9/pdb
• EMDB information: 50389
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, DECANE, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ... (15 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 282674.65

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Etomidate in the long-lived symmetric desensitised state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)