9E3D

Cryo-EM structure of DNMT 3A2/3B3 tetramer in complex with a di-nucleosome with K120R mutant H2B

Summary for 9E3D

• Entry DOI: 10.2210/pdb9e3d/pdb
• Related: 9E00 9E05
• EMDB information: 47479
• Descriptor: Histone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, Histone H4, ... (10 entities in total)
• Functional Keywords: dnmt 3a2/3b3, di-nucleosome, methylation, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 22
• Total formula weight: 745696.32

Authors

Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.,Jones, P. (deposition date: 2024-10-23, release date: 2026-02-18)

• Primary citation: Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.,Jones, P.; The structural basis for de novo DNA methylation in chromatin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)