9E00

Cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Summary for 9E00

• Entry DOI: 10.2210/pdb9e00/pdb
• EMDB information: 47344
• Descriptor: Histone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, Histone H4, ... (10 entities in total)
• Functional Keywords: dnmt3a2, dnmt3b3, dna methylation, di-nucleosome, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 26
• Total formula weight: 1076204.66

Authors

Xie, X.,Zhou, X.E.,Worden, E.J.,Jones, P.A. (deposition date: 2024-10-17, release date: 2026-02-25)

• Primary citation: Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.J.,Jones, P.A.; The structure basis for de novo DNA methylation in chromatin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.75 Å)