9E05

The consensus model of the cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Summary for 9E05

Entry DOI	10.2210/pdb9e05/pdb
Related	9E00
EMDB information	47344 47349
Descriptor	Histone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, Histone H4, ... (10 entities in total)
Functional Keywords	dnmt3a2, dnmt3b3, dna methylation, di-nucleosome, dna binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	26
Total formula weight	1076793.34
Authors	Xie, X.,Zhou, X.E.,Worden, E.J.,Jones, P.A. (deposition date: 2024-10-17, release date: 2026-02-18)
Primary citation	Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.J.,Jones, P.A. The structure basis for de novo DNA methylation in chromatin To Be Published,
Experimental method	ELECTRON MICROSCOPY (8 Å)

Structure validation