9CQ3

The gap-filling complex with Pol mu engaged in the NHEJ pathway

Summary for 9CQ3

• Entry DOI: 10.2210/pdb9cq3/pdb
• EMDB information: 45807
• Descriptor: X-ray repair cross-complementing protein 6, DNA (37-MER), DNA-directed DNA/RNA polymerase mu, ... (13 entities in total)
• Functional Keywords: nhej, dna gap, fill-in synthesis, ligation, xlf, paxx, polymerase mu, dna repair, ligase iv, ligase-transferase-dna complex, ligase/transferase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 20
• Total formula weight: 969322.24

Authors

Li, J.,Liu, L.,Gellert, M.,Yang, W. (deposition date: 2024-07-19, release date: 2025-04-23, Last modification date: 2025-06-11)

• Primary citation: Liu, L.,Li, J.,Cisneros-Aguirre, M.,Merkell, A.,Stark, J.M.,Gellert, M.,Yang, W.; Dynamic assemblies and coordinated reactions of non-homologous end joining; Nature, 2025; DOI: 10.1038/s41586-025-09078-9

Experimental method

ELECTRON MICROSCOPY (2.8 Å)