9B3C

type 2 KD-mxyl filament of miniature tau macrocycle derived from 4R tauopathic fold

Summary for 9B3C

• Entry DOI: 10.2210/pdb9b3c/pdb
• EMDB information: 44134
• Descriptor: Microtubule-associated protein tau, GLY-SER-VAL-GLN-ILE-VAL-TYR, AMINO GROUP, ... (4 entities in total)
• Functional Keywords: tauopathies, neurodegenerative disorders, seed-competent miniature tau macrocycle, protein fibril
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 30
• Total formula weight: 46945.42

Authors

Xu, X.,Angera, J.I.,Rajewski, H.B.,Jiang, W.,Del Valle, R.J. (deposition date: 2024-03-18, release date: 2025-03-26)

• Primary citation: Xu, X.,Angera, J.I.,Rajewski, H.B.,Jiang, W.,Del Valle, R.J.; Structure-based design of seed-competent proteomimetic macrocycles derived from 4R tauopathic folds; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.95 Å)