9B3C
type 2 KD-mxyl filament of miniature tau macrocycle derived from 4R tauopathic fold
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, AA, B, C, CA... (A, G, M, S, C...) | Microtubule-associated protein tau | polymer | 22 | 2242.6 | 15 | UniProt (P10636) Pfam (PF00418) | Homo sapiens | Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau |
| 2 | BA, DA, E, F, G... (B, H, N, T, D...) | GLY-SER-VAL-GLN-ILE-VAL-TYR | polymer | 7 | 764.9 | 15 | Homo sapiens | ||
| 3 | AB, CB, EA, EB, GA... (W, Y, A, a, G...) | AMINO GROUP | non-polymer | 16.0 | 15 | Chemie (NH2) | |||
| 4 | BB, DB, FA, FB, HA... (W, Y, A, a, G...) | 1,3-dimethylbenzene | non-polymer | 106.2 | 15 | Chemie (8VH) |
Sequence modifications
A, G, M, S, C, I, O, U, E, K, Q, W, Y, a, c: 295 - 313 (UniProt: P10636)
| PDB | External Database | Details |
|---|---|---|
| Ace 293 | - | expression tag |
| Cys 294 | - | expression tag |
| Cys 314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 45112.6 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 1832.8 | |
| All* | Total formula weight | 46945.4 |
