9B3C

type 2 KD-mxyl filament of miniature tau macrocycle derived from 4R tauopathic fold

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	SITE: Not glycated => ECO:0000269|PubMed:9326300

Chain	Residue	Details
A	LYS298
C	LYS311
I	LYS298
I	LYS311
O	LYS298
O	LYS311
U	LYS298
U	LYS311
E	LYS298
E	LYS311
K	LYS298
A	LYS311
K	LYS311
Q	LYS298
Q	LYS311
W	LYS298
W	LYS311
Y	LYS298
Y	LYS311
a	LYS298
a	LYS311
c	LYS298
G	LYS298
c	LYS311
G	LYS311
M	LYS298
M	LYS311
S	LYS298
S	LYS311
C	LYS298

---

site_id	SWS_FT_FI2
Number of Residues	30
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P10637

Chain	Residue	Details
A	LYS298
C	LYS311
I	LYS298
I	LYS311
O	LYS298
O	LYS311
U	LYS298
U	LYS311
E	LYS298
E	LYS311
K	LYS298
A	LYS311
K	LYS311
Q	LYS298
Q	LYS311
W	LYS298
W	LYS311
Y	LYS298
Y	LYS311
a	LYS298
a	LYS311
c	LYS298
G	LYS298
c	LYS311
G	LYS311
M	LYS298
M	LYS311
S	LYS298
S	LYS311
C	LYS298

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	MOD_RES: Phosphoserine; by PHK => ECO:0000269|PubMed:7706316, ECO:0000269|PubMed:8999860

Chain	Residue	Details
A	SER305
K	SER305
Q	SER305
W	SER305
Y	SER305
a	SER305
c	SER305
G	SER305
M	SER305
S	SER305
C	SER305
I	SER305
O	SER305
U	SER305
E	SER305

---

site_id	SWS_FT_FI4
Number of Residues	15
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P10637

Chain	Residue	Details
A	LYS298
K	LYS298
Q	LYS298
W	LYS298
Y	LYS298
a	LYS298
c	LYS298
G	LYS298
M	LYS298
S	LYS298
C	LYS298
I	LYS298
O	LYS298
U	LYS298
E	LYS298

---

site_id	SWS_FT_FI5
Number of Residues	30
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); in PHF-tau => ECO:0000269|PubMed:16443603

Chain	Residue	Details
C	LYS311
I	LYS311
O	LYS311
U	LYS311
E	LYS311
A	LYS311
K	LYS311
Q	LYS311
W	LYS311
Y	LYS311
a	LYS311
c	LYS311
G	LYS311
M	LYS311
S	LYS311

---