8Z9O

Cryo-EM structure of human GPR4-Gs complex

Summary for 8Z9O

• Entry DOI: 10.2210/pdb8z9o/pdb
• EMDB information: 39865
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: gpcr, class a, gpr4-gs, cryo-em, protein sensing, active state, membrane protein/immune system, membrane protein-immune system complex
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 5
• Total formula weight: 135836.88

Authors

Chen, L.N.,Mao, C.Y.,Cheng, S.Z.,Liu, Y.F.,Fu, Y.F.,Ma, X.Y.,Xu, P.,Ji, S.Y.,Wang, W.W.,Shen, D.D.,Zhang, H.B.,Shen, Q.Y.,Chai, R.,Zhang, M.,Yang, L.,Han, F.,Mao, C.Y.,Cai, X.J.,Zhang, Y. (deposition date: 2024-04-23, release date: 2025-07-16)

• Primary citation: Chen, L.N.,Zhou, H.,Xi, K.; Cryo-EM structure of human GPR4-Gs complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.4 Å)