8XI9

Crystal structure of FRB-FKBP fusion protein in complex with rapamycin

Summary for 8XI9

• Entry DOI: 10.2210/pdb8xi9/pdb
• Descriptor: FRB-FKBP fusion protein, RAPAMYCIN IMMUNOSUPPRESSANT DRUG (3 entities in total)
• Functional Keywords: rapamycin, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 24244.86

Authors

Inobe, T.,Sakaguchi, R.,Obita, T.,Mukaiyama, A.,Yokoyama, T.,Mizuguchi, M.,Akiyama, S. (deposition date: 2023-12-19, release date: 2024-08-07)

• Primary citation: Inobe, T.,Sakaguchi, R.,Obita, T.,Mukaiyama, A.,Koike, S.,Yokoyama, T.,Mizuguchi, M.,Akiyama, S.; Structural insights into rapamycin-induced oligomerization of a FRB-FKBP fusion protein.; Febs Lett., 2024; PubMed: 39031920; DOI: 10.1002/1873-3468.14986

Experimental method

X-RAY DIFFRACTION (1.85 Å)