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8XI9

Crystal structure of FRB-FKBP fusion protein in complex with rapamycin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
FRB-FKBP fusion proteinpolymer20223330.71UniProt (P42345)
UniProt (P62942)
Pfam (PF08771)
Pfam (PF00254)
Homo sapiens (human)
2B
(A)
RAPAMYCIN IMMUNOSUPPRESSANT DRUGnon-polymer914.21Chemie (RAP)
3C
(A)
waterwater18.0115Chemie (HOH)
Sequence modifications
A: 3 - 94 (UniProt: P42345)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Gly 2-expression tag
A: 95 - 202 (UniProt: P62942)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23330.7
Non-Polymers*Number of molecules1
Total formula weight914.2
All*Total formula weight24244.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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