8XI9
Crystal structure of FRB-FKBP fusion protein in complex with rapamycin
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P26883 |
| Chain | Residue | Details |
| A | LYS147 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 362 |
| Chain | Residue | Details |
| A | TYR121 | electrostatic destabiliser, steric role |
| A | PHE131 | electrostatic destabiliser, polar/non-polar interaction, steric role |
| A | ASP132 | electrostatic stabiliser, steric role |
| A | ILE151 | electrostatic stabiliser, steric role |
| A | TYR177 | electrostatic stabiliser, steric role |
| A | PHE194 | electrostatic destabiliser, polar/non-polar interaction, steric role |
