8XCH

SARS-CoV-2 Replication-Transcription Complex has a dimer-of-dimeric architecture (ddRTC) in pre-capping initiation.

Summary for 8XCH

• Entry DOI: 10.2210/pdb8xch/pdb
• EMDB information: 38243
• Descriptor: Replicase polyprotein 1ab, PHOSPHATE ION, Non-structural protein 8, ... (10 entities in total)
• Functional Keywords: sars-cov-2, replication-transcription complex, helicase, rna unwinding, cryo-em, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 32
• Total formula weight: 1283424.40

Authors

Yan, L.,Lou, Z. (deposition date: 2023-12-09, release date: 2025-06-11)

• Primary citation: Yan, L.,Lou, Z.; Structural basis for template-product RNA duplex unwinding by SARS-CoV-2 helicase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)