Summary for 8VC0
| Entry DOI | 10.2210/pdb8vc0/pdb |
| Descriptor | Capsid protein p24, N-[(1S)-1-{(3M)-3-{4-chloro-3-[(cyclopropanesulfonyl)amino]-1-(2,2-difluoroethyl)-1H-indazol-7-yl}-6-[3-(methanesulfonyl)-3-methylbut-1-yn-1-yl]pyridin-2-yl}-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-3-(difluoromethyl)-5,5-difluoro-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide (2 entities in total) |
| Functional Keywords | pentamer, capsid, hiv, viral protein |
| Biological source | Human immunodeficiency virus 1 |
| Total number of polymer chains | 10 |
| Total formula weight | 264346.22 |
| Authors | Piacentini, J.,Ganser-Pornillos, B.K.,Pornillos, O. (deposition date: 2023-12-13, release date: 2025-03-19) |
| Primary citation | Piacentini, J.,Ganser-Pornillos, B.K.,Pornillos, O. Structure of disulfide-stabilized HIV-1 CA pentamer in complex with the ultra-potent capsid inhibitor, GS-CA1 To Be Published, |
| Experimental method | X-RAY DIFFRACTION (3.46 Å) |
Structure validation
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