8V2O
Cryo-EM Structure of Wildtype Smooth Muscle Gamma Actin (ACTG2)
Summary for 8V2O
| Entry DOI | 10.2210/pdb8v2o/pdb |
| EMDB information | 42918 |
| Descriptor | Actin, gamma-enteric smooth muscle, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | filament, actin, smooth muscle, cytosolic protein, structural protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 5 |
| Total formula weight | 211936.61 |
| Authors | Palmer, N.J.,Carman, P.J.,Ceron, R.H.,Dominguez, R. (deposition date: 2023-11-23, release date: 2024-05-01, Last modification date: 2024-06-12) |
| Primary citation | Ceron, R.H.,Baez-Cruz, F.A.,Palmer, N.J.,Carman, P.J.,Boczkowska, M.,Heuckeroth, R.O.,Ostap, E.M.,Dominguez, R. Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy. Sci Adv, 10:eadn6615-eadn6615, 2024 Cited by PubMed: 38820162DOI: 10.1126/sciadv.adn6615 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.45 Å) |
Structure validation
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