8UM5

X-ray structure of human SHIP1 Ptase-C2 domains covalently bound to TREAT-AD (TAD) compound TAD-58547

Summary for 8UM5

• Entry DOI: 10.2210/pdb8um5/pdb
• Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, 5-(1,4-oxazepan-4-yl)-6-propanoylpyridine-2-carbonitrile, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: ship1, inpp5d, alzheimer's disase, treat-ad, inhibitor, lipid binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 53371.28

Authors

Mesecar, A.D.,Hamdani, A.K. (deposition date: 2023-10-17, release date: 2024-10-23)

• Primary citation: Hamdani, A.K.,Mesecar, A.D.; X-ray structure of human SHIP1 Ptase-C2 domains covalently bound to TREAT-AD (TAD) compound TAD-58547; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.86 Å)