8UM5

X-ray structure of human SHIP1 Ptase-C2 domains covalently bound to TREAT-AD (TAD) compound TAD-58547

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016791	molecular_function	phosphatase activity
A	0046856	biological_process	phosphatidylinositol dephosphorylation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	316
Details	Domain: {"description":"5-PPase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01427","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01427","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01427","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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