8TTA

Structure of retromer VPS29-VPS35 (483-796) complexed with Fam21A repeat 21 (1328-1341)

Summary for 8TTA

Entry DOI	10.2210/pdb8tta/pdb
Descriptor	Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, SER-ASN-ILE-PHE-ASP-ASP-PRO-LEU-ASN-ALA-PHE-GLY-GLY-GLN, ... (7 entities in total)
Functional Keywords	vps29, vps35, fam21, retromer, wash complex, endosome, protein transport, endocytosis
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	6
Total formula weight	118884.21
Authors	Chen, K.-E.,Guo, Q.,Collins, B.M. (deposition date: 2023-08-13, release date: 2024-08-21)
Primary citation	Guo, Q.,Chen, K.E.,Gimenez-Andres, M.,Jellett, A.P.,Gao, Y.,Simonetti, B.,Liu, M.,Danson, C.M.,Heesom, K.J.,Cullen, P.J.,Collins, B.M. Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex. Proc.Natl.Acad.Sci.USA, 121:e2405041121-e2405041121, 2024 Cited by PubMed: 39116126 DOI: 10.1073/pnas.2405041121 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.46 Å)

Structure validation