8TTA
Structure of retromer VPS29-VPS35 (483-796) complexed with Fam21A repeat 21 (1328-1341)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Vacuolar protein sorting-associated protein 29 | polymer | 192 | 21626.8 | 2 | UniProt (Q9QZ88) Pfam (PF12850) | Mus musculus (house mouse) | Vesicle protein sorting 29 |
| 2 | B, D (B, D) | Vacuolar protein sorting-associated protein 35 | polymer | 314 | 36093.0 | 2 | UniProt (Q9EQH3) Pfam (PF03635) | Mus musculus (house mouse) | Maternal-embryonic 3,Vesicle protein sorting 35 |
| 3 | E, F (E, F) | SER-ASN-ILE-PHE-ASP-ASP-PRO-LEU-ASN-ALA-PHE-GLY-GLY-GLN | polymer | 14 | 1494.6 | 2 | UniProt (Q641Q2) | Homo sapiens | WASH complex subunit 2A |
| 4 | G, H (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | I, K (C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | J (D) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 182 (UniProt: Q9QZ88)
| PDB | External Database | Details |
|---|---|---|
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Pro -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Thr -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Arg 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 118428.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 455.5 | |
| All* | Total formula weight | 118884.2 |
