8TTA

Structure of retromer VPS29-VPS35 (483-796) complexed with Fam21A repeat 21 (1328-1341)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Vacuolar protein sorting-associated protein 29	polymer	192	21626.8	2	UniProt (Q9QZ88) In PDB	Mus musculus (house mouse)	Vesicle protein sorting 29
2	B, D	Vacuolar protein sorting-associated protein 35	polymer	314	36093.0	2	UniProt (Q9EQH3) In PDB	Mus musculus (house mouse)	Maternal-embryonic 3,Vesicle protein sorting 35
3	E, F	SER-ASN-ILE-PHE-ASP-ASP-PRO-LEU-ASN-ALA-PHE-GLY-GLY-GLN	polymer	14	1494.6	2	UniProt (Q641Q2) In PDB	Homo sapiens	WASH complex subunit 2A
4	B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	C, D	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
6	D	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
7		water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, C: 1 - 182 (UniProt: Q9QZ88)

PDB	External Database	Details
Gly -9	-	expression tag
Ser -8	-	expression tag
Pro -7	-	expression tag
Glu -6	-	expression tag
Phe -5	-	expression tag
Gly -4	-	expression tag
Thr -3	-	expression tag
Arg -2	-	expression tag
Asp -1	-	expression tag
Arg 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	118428.7
Non-Polymers*	Number of molecules	5
	Total formula weight	455.5
All*	Total formula weight	118884.2

*Water molecules are not included.