8TGA
Complex of NPR1 ectodomain and REGN5381 Fab in an active-like state with no ANP bound
Summary for 8TGA
Entry DOI | 10.2210/pdb8tga/pdb |
EMDB information | 41234 |
Descriptor | Atrial natriuretic peptide receptor 1, REGN5381 Fab light chain, REGN5381 Fab heavy chain (3 entities in total) |
Functional Keywords | atrial natriuretic peptide, antibody, activator, pulmonary hypertension, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 200812.78 |
Authors | |
Primary citation | Franklin, M.C.,Romero Hernandez, A. Complex of NPR1 ectodomain and REGN5381 Fab in an active-like state with no ANP bound To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.65 Å) |
Structure validation
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