8TAS

PRC2 monomer bound to nucleosome

Summary for 8TAS

Entry DOI	10.2210/pdb8tas/pdb
EMDB information	41110 41141
Descriptor	Polycomb protein SUZ12, Histone-binding protein RBBP4, Zinc finger protein AEBP2, ... (12 entities in total)
Functional Keywords	histone methyl transferase, gene repression, epigenetics, chromatin, gene regulation
Biological source	Homo sapiens (human) More
Total number of polymer chains	15
Total formula weight	533576.07
Authors	Sauer, P.V.,Pavlenko, E.,Nogales, E.,Poepsel, S. (deposition date: 2023-06-27, release date: 2024-09-25)
Primary citation	Sauer, P.V.,Pavlenko, E.,Cookis, T.,Zirden, L.C.,Renn, J.,Singhal, A.,Hunold, P.,Hoehne-Wiechmann, M.N.,van Ray, O.,Kaschani, F.,Kaiser, M.,Hansel-Hertsch, R.,Sanbonmatsu, K.Y.,Nogales, E.,Poepsel, S. Activation of automethylated PRC2 by dimerization on chromatin Mol.Cell, 2024 Cited by DOI: 10.1016/j.molcel.2024.08.025 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation