8S0L

Crystal structure of the TMPRSS2 zymogen in complex with the nanobody A07

Summary for 8S0L

• Entry DOI: 10.2210/pdb8s0l/pdb
• Related: 8S0M 8S0N
• Descriptor: Transmembrane protease serine 2, Nanobody A07, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: protease, nanobody, inhibitor, zymogen, protein binding, protease-nanobody inhibitor complex, protease/nanobody inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 59970.97

Authors

Duquerroy, S.,Fernandez, I.,Rey, F. (deposition date: 2024-02-14, release date: 2024-06-26)

• Primary citation: Fernandez, I.,Saunders, N.,Duquerroy, S.,Boland, W.H.,Arbabian, A.,Baquero, E.,Lafaye, P.,Haouz, A.,Buchrieser, J.,Schwartz, O.,Rey, F.; Structural insights into TMPRSS2 maturation and HKU1 binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)