8RP8

Structure of K2 Fab in complex with human CD47 ECD

Summary for 8RP8

• Entry DOI: 10.2210/pdb8rp8/pdb
• Descriptor: K2 Fab heavy chain, K2 Fab light chain, Leukocyte surface antigen CD47, ... (7 entities in total)
• Functional Keywords: immune system, fab, glycoprotein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 125099.30

Authors

Laursen, M.,Kelpsas, V.,Rose, N. (deposition date: 2024-01-12, release date: 2024-06-19)

• Primary citation: Malinge, P.,Chauchet, X.,Bourguignon, J.,Bosson, N.,Calloud, S.,Bautzova, T.,Borlet, M.,Laursen, M.,Kelpsas, V.,Rose, N.,Gueneau, F.,Ravn, U.,Magistrelli, G.,Fischer, N.; Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1.; Mabs, 16:2362432-2362432, 2024; PubMed: 38849989; DOI: 10.1080/19420862.2024.2362432

Experimental method

X-RAY DIFFRACTION (2 Å)