8RMN

Cryo-EM structure of a dimer of decameric human CALHM4 in complex with synthetic nanobody SbC4

Summary for 8RMN

• Entry DOI: 10.2210/pdb8rmn/pdb
• EMDB information: 19365
• Descriptor: Calcium homeostasis modulator protein 4, Synthetic nanobody SbC4 (2 entities in total)
• Functional Keywords: ion channel, large pore channels, sybody, calhm, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 40
• Total formula weight: 1031898.48

Authors

Peter, M.,Drozdzyk, K.,Dutzler, R. (deposition date: 2024-01-08, release date: 2024-06-19)

• Primary citation: Drozdzyk, K.,Peter, M.,Dutzler, R.; Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)