8RMN
Cryo-EM structure of a dimer of decameric human CALHM4 in complex with synthetic nanobody SbC4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D, E, F... (A, B, C, D, E...) | Calcium homeostasis modulator protein 4 | polymer | 322 | 35981.7 | 20 | UniProt (Q5JW98) Pfam (PF14798) | Homo sapiens (human) | Protein FAM26D |
| 2 | AA, B, BA, CA, DA... (U, V, W, X, Y...) | Synthetic nanobody SbC4 | polymer | 143 | 15613.3 | 20 | synthetic construct |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T: 2 - 314 (UniProt: Q5JW98)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 1 | - | expression tag |
| Ala 315 | - | expression tag |
| Leu 316 | - | expression tag |
| Glu 317 | - | expression tag |
| Val 318 | - | expression tag |
| Leu 319 | - | expression tag |
| Phe 320 | - | expression tag |
| Gln 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 40 |
| Total formula weight | 1031898.5 | |
| All* | Total formula weight | 1031898.5 |
