8QB2
Crystal Structure of BRPF1 bromodomain in complex with acetyl-pyrrole derivative compound 79
Summary for 8QB2
Entry DOI | 10.2210/pdb8qb2/pdb |
Related | 7QYO 8QAN 8QAZ 8QB0 |
Descriptor | Peregrin, 1-[2-methyl-4-(3-methylbutyl)-5-(2-piperazin-1-yl-1,3-thiazol-4-yl)-1~{H}-pyrrol-3-yl]ethanone, NITRATE ION, ... (4 entities in total) |
Functional Keywords | four helical bundle, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 14126.22 |
Authors | |
Primary citation | Cazzanelli, G.,Dalle Vedove, A.,Caflisch, A.,Lolli, G. Dual BET/BRPF1 inhibitors induce morphological alteration and cellular death in various human cancer cell lines To be published, |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
Download full validation report