8QB2
Crystal Structure of BRPF1 bromodomain in complex with acetyl-pyrrole derivative compound 79
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peregrin | polymer | 116 | 13703.7 | 1 | UniProt (P55201) Pfam (PF00439) In PDB | Homo sapiens (human) | Bromodomain and PHD finger-containing protein 1,Protein Br140 |
| 2 | A | 1-[2-methyl-4-(3-methylbutyl)-5-(2-piperazin-1-yl-1,3-thiazol-4-yl)-1~{H}-pyrrol-3-yl]ethanone | non-polymer | 360.5 | 1 | Chemie (GKI) | |||
| 3 | A | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 4 | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 626 - 740 (UniProt: P55201)
| PDB | External Database | Details |
|---|---|---|
| Ser 625 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13703.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 422.5 | |
| All* | Total formula weight | 14126.2 |
