8Q4D

IstA-IstB(E167Q) Strand Transfer Complex

This is a non-PDB format compatible entry.

Summary for 8Q4D

• Entry DOI: 10.2210/pdb8q4d/pdb
• Related: 5BQ5 8B4H
• EMDB information: 15848 18136 18144
• Descriptor: Putative transposase for insertion sequence element IS5376, Insertion sequence IS5376 putative ATP-binding protein, DNA (118-MER) / TIR-transferred strand, ... (8 entities in total)
• Functional Keywords: dna transposition, dna integration, transposon, transpososome, holo-transpososome, insertion sequence, is21, ista, istb, dde transposase, dde domain, aaa+ atpase, dna strand transfer complex, stc, dna binding protein
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 30
• Total formula weight: 907125.52

Authors

de la Gandara, A.,Spinola-Amilibia, M.,Araujo-Bazan, L.,Nunez-Ramirez, R.,Berger, J.M.,Arias-Palomo, E. (deposition date: 2023-08-06, release date: 2024-07-10)

• Primary citation: de la Gandara, A.,Spinola-Amilibia, M.,Araujo-Bazan, L.,Nunez-Ramirez, R.,Berger, J.M.,Arias-Palomo, E.; Molecular basis for transposase activation by a dedicated AAA+ ATPase.; Nature, 630:1003-1011, 2024; PubMed: 38926614; DOI: 10.1038/s41586-024-07550-6

Experimental method

ELECTRON MICROSCOPY (3.62 Å)