Summary for 8Q0N
Entry DOI | 10.2210/pdb8q0n/pdb |
Related | 8PWL |
EMDB information | 18056 |
Descriptor | E3 ubiquitin-protein ligase HACE1, Ras-related C3 botulinum toxin substrate 1, iodoacetic acid, ... (4 entities in total) |
Functional Keywords | e3, ubiquitin ligase, small gtpase, crosslink, sia, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 124409.46 |
Authors | Wolter, M.,Duering, J.,Dienemann, C.,Lorenz, S. (deposition date: 2023-07-28, release date: 2024-01-10, Last modification date: 2024-02-28) |
Primary citation | During, J.,Wolter, M.,Toplak, J.J.,Torres, C.,Dybkov, O.,Fokkens, T.J.,Bohnsack, K.E.,Urlaub, H.,Steinchen, W.,Dienemann, C.,Lorenz, S. Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1. Nat.Struct.Mol.Biol., 31:364-377, 2024 Cited by PubMed: 38332367DOI: 10.1038/s41594-023-01203-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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