8PVB

Structure of GABAAR determined by cryoEM at 100 keV

Summary for 8PVB

• Entry DOI: 10.2210/pdb8pvb/pdb
• EMDB information: 17960
• Descriptor: Gamma-aminobutyric acid receptor subunit beta-3, Megabody Mb25, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: pentameric ligand-gated ion channel, neurotrasmitter receptor, gaba(a) receptor, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 104602.05

Authors

McMullan, G.,Naydenova, K.,Mihaylov, D.,Peet, M.J.,Wilson, H.,Yamashita, K.,Dickerson, J.L.,Chen, S.,Cannone, G.,Lee, Y.,Hutchings, K.A.,Gittins, O.,Sobhy, M.,Wells, T.,El-Gomati, M.M.,Dalby, J.,Meffert, M.,Schulze-Briese, C.,Henderson, R.,Russo, C.J. (deposition date: 2023-07-17, release date: 2023-11-29, Last modification date: 2024-01-31)

• Primary citation: McMullan, G.,Naydenova, K.,Mihaylov, D.,Yamashita, K.,Peet, M.J.,Wilson, H.,Dickerson, J.L.,Chen, S.,Cannone, G.,Lee, Y.,Hutchings, K.A.,Gittins, O.,Sobhy, M.A.,Wells, T.,El-Gomati, M.M.,Dalby, J.,Meffert, M.,Schulze-Briese, C.,Henderson, R.,Russo, C.J.; Structure determination by cryoEM at 100 keV.; Proc.Natl.Acad.Sci.USA, 120:e2312905120-e2312905120, 2023; PubMed: 38011573; DOI: 10.1073/pnas.2312905120

Experimental method

ELECTRON MICROSCOPY (3.6 Å)