8P2S
Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/dTTP/GTP-bound state
Summary for 8P2S
Entry DOI | 10.2210/pdb8p2s/pdb |
Related | 8P23 8P27 8P28 8P2C 8P2D 8P39 |
EMDB information | 17357 17358 17359 17360 17361 17373 17385 |
Descriptor | Anaerobic ribonucleoside-triphosphate reductase, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | ribonucleotide reductase glycyl radical enzyme allosteric regulation nucleotide biosynthesis, biosynthetic protein |
Biological source | Segatella copri |
Total number of polymer chains | 2 |
Total formula weight | 170873.64 |
Authors | Bimai, O.,Banerjee, I.,Sjoberg, B.M.,Logan, D.T. (deposition date: 2023-05-16, release date: 2023-09-13) |
Primary citation | Bimai, O.,Banerjee, I.,Rozman Grinberg, I.,Huang, P.,Lundin, D.,Sjoberg, B.M.,Logan, D.T. Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023 |
Experimental method | ELECTRON MICROSCOPY (2.4 Å) |
Structure validation
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