8P23

Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/CTP-bound state

8P23 の概要

• エントリーDOI: 10.2210/pdb8p23/pdb
• 関連するPDBエントリー: 8P27 8P28 8P2C 8P2D 8P2S 8P39
• EMDBエントリー: 17357 17358 17359 17360 17361 17373 17385
• 分子名称: Anaerobic ribonucleoside-triphosphate reductase, ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: ribonucleotide reductase glycyl radical enzyme allosteric regulation nucleotide biosynthesis, biosynthetic protein
• 由来する生物種: Prevotella copri
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 171849.40

構造登録者

Banerjee, I.,Bimai, O.,Sjoberg, B.M.,Logan, D.T. (登録日: 2023-05-14, 公開日: 2023-08-30)

• 主引用文献: Bimai, O.,Banerjee, I.,Rozman Grinberg, I.,Huang, P.,Lundin, D.,Sjoberg, B.M.,Logan, D.T.; Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site; Elife, 2023; DOI: 10.7554/eLife.89292.1

実験手法

ELECTRON MICROSCOPY (3.17 Å)