8GRQ

Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome

Summary for 8GRQ

• Entry DOI: 10.2210/pdb8grq/pdb
• EMDB information: 34212
• Descriptor: Histone H3, ZINC ION, Histone H4, ... (10 entities in total)
• Functional Keywords: nucleosome, brca1/bard1, brca1, bard1, h2ak127, h2ak127-ubch5c-ub, nuclear protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 13
• Total formula weight: 235960.68

Authors

Ai, H.S.,Zebin, T.,Zhiheng, D.,Jiakun, T.,Liying, Z.,Jia-Bin, L.,Man, P.,Liu, L. (deposition date: 2022-09-02, release date: 2023-04-12, Last modification date: 2024-07-03)

• Primary citation: Ai, H.S.,Tong, Z.,Deng, Z.,Tian, J.,Zhang, L.,Sun, M.,Du, Y.,Xu, Z.,Shi, Q.,Liang, L.,Zheng, Q.,Li, J.B.,Pan, M.,Liu, L.; Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.; Chem, 2023; DOI: 10.1016/j.chempr.2023.01.012

Experimental method

ELECTRON MICROSCOPY (3.87 Å)