8GNK

CryoEM structure of cytosol-facing, substrate-bound ratGAT1

Summary for 8GNK

Entry DOI	10.2210/pdb8gnk/pdb
EMDB information	34167
Descriptor	Sodium- and chloride-dependent GABA transporter 1, Fragment antigen binding light chain, fragment antigen binding 9D5 heavy chain, ... (10 entities in total)
Functional Keywords	neurotransmitter sodium symporter, gaba transporter, solute carrier 6, secondary active transport, membrane protein
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	3
Total formula weight	113784.63
Authors	Nayak, S.R.,Joseph, D.,Penmatsa, A. (deposition date: 2022-08-24, release date: 2023-05-31, Last modification date: 2023-11-15)
Primary citation	Nayak, S.R.,Joseph, D.,Hofner, G.,Dakua, A.,Athreya, A.,Wanner, K.T.,Kanner, B.I.,Penmatsa, A. Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism. Nat.Struct.Mol.Biol., 30:1023-1032, 2023 Cited by PubMed: 37400654 DOI: 10.1038/s41594-023-01011-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation