8GBJ

Cryo-EM structure of a human BCDX2/ssDNA complex

Summary for 8GBJ

• Entry DOI: 10.2210/pdb8gbj/pdb
• Related: 8FAZ
• EMDB information: 28961 29917
• Descriptor: DNA repair protein RAD51 homolog 2, DNA repair protein RAD51 homolog 3, DNA repair protein RAD51 homolog 4, ... (6 entities in total)
• Functional Keywords: dna binding protein, atp binding domain, homologous recombination, rad51 paralog, recombination, ssdna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 159596.29

Authors

Jia, L.,Wasmuth, E.V.,Ruben, E.A.,Sung, P.,Rawal, Y.,Greene, E.C.,Meir, A.,Olsen, S.K. (deposition date: 2023-02-26, release date: 2023-06-21, Last modification date: 2023-08-02)

• Primary citation: Rawal, Y.,Jia, L.,Meir, A.,Zhou, S.,Kaur, H.,Ruben, E.A.,Kwon, Y.,Bernstein, K.A.,Jasin, M.,Taylor, A.B.,Burma, S.,Hromas, R.,Mazin, A.V.,Zhao, W.,Zhou, D.,Wasmuth, E.V.,Greene, E.C.,Sung, P.,Olsen, S.K.; Structural insights into BCDX2 complex function in homologous recombination.; Nature, 619:640-649, 2023; PubMed: 37344589; DOI: 10.1038/s41586-023-06219-w

Experimental method

ELECTRON MICROSCOPY (3.11 Å)