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8GBJ

Cryo-EM structure of a human BCDX2/ssDNA complex

Functional Information from GO Data
ChainGOidnamespacecontents
B0000400molecular_functionfour-way junction DNA binding
B0000724biological_processdouble-strand break repair via homologous recombination
B0001701biological_processin utero embryonic development
B0001832biological_processblastocyst growth
B0003677molecular_functionDNA binding
B0003690molecular_functiondouble-stranded DNA binding
B0003697molecular_functionsingle-stranded DNA binding
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005657cellular_componentreplication fork
B0006281biological_processDNA repair
B0006310biological_processDNA recombination
B0007131biological_processreciprocal meiotic recombination
B0008094molecular_functionATP-dependent activity, acting on DNA
B0008284biological_processpositive regulation of cell population proliferation
B0010971biological_processpositive regulation of G2/M transition of mitotic cell cycle
B0016887molecular_functionATP hydrolysis activity
B0033063cellular_componentRad51B-Rad51C-Rad51D-XRCC2 complex
B0061053biological_processsomite development
B0140664molecular_functionATP-dependent DNA damage sensor activity
C0000400molecular_functionfour-way junction DNA binding
C0000707biological_processmeiotic DNA recombinase assembly
C0000722biological_processtelomere maintenance via recombination
C0000724biological_processdouble-strand break repair via homologous recombination
C0003677molecular_functionDNA binding
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005657cellular_componentreplication fork
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005829cellular_componentcytosol
C0006281biological_processDNA repair
C0006310biological_processDNA recombination
C0007062biological_processsister chromatid cohesion
C0007066biological_processfemale meiosis sister chromatid cohesion
C0007131biological_processreciprocal meiotic recombination
C0007141biological_processmale meiosis I
C0007283biological_processspermatogenesis
C0008821molecular_functioncrossover junction DNA endonuclease activity
C0010971biological_processpositive regulation of G2/M transition of mitotic cell cycle
C0030054cellular_componentcell junction
C0033063cellular_componentRad51B-Rad51C-Rad51D-XRCC2 complex
C0033065cellular_componentRad51C-XRCC3 complex
C0043231cellular_componentintracellular membrane-bounded organelle
C0048471cellular_componentperinuclear region of cytoplasm
C0140664molecular_functionATP-dependent DNA damage sensor activity
D0000400molecular_functionfour-way junction DNA binding
D0000722biological_processtelomere maintenance via recombination
D0000723biological_processtelomere maintenance
D0000724biological_processdouble-strand break repair via homologous recombination
D0000781cellular_componentchromosome, telomeric region
D0003677molecular_functionDNA binding
D0003697molecular_functionsingle-stranded DNA binding
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005657cellular_componentreplication fork
D0005694cellular_componentchromosome
D0005737cellular_componentcytoplasm
D0005813cellular_componentcentrosome
D0005815cellular_componentmicrotubule organizing center
D0005856cellular_componentcytoskeleton
D0006281biological_processDNA repair
D0006310biological_processDNA recombination
D0006974biological_processDNA damage response
D0007131biological_processreciprocal meiotic recombination
D0008094molecular_functionATP-dependent activity, acting on DNA
D0016887molecular_functionATP hydrolysis activity
D0033063cellular_componentRad51B-Rad51C-Rad51D-XRCC2 complex
D0036297biological_processinterstrand cross-link repair
D0042148biological_processDNA strand invasion
D0043015molecular_functiongamma-tubulin binding
D0051276biological_processchromosome organization
D0051726biological_processregulation of cell cycle
D0140664molecular_functionATP-dependent DNA damage sensor activity
X0000278biological_processmitotic cell cycle
X0000400molecular_functionfour-way junction DNA binding
X0000724biological_processdouble-strand break repair via homologous recombination
X0001701biological_processin utero embryonic development
X0001756biological_processsomitogenesis
X0003677molecular_functionDNA binding
X0005515molecular_functionprotein binding
X0005524molecular_functionATP binding
X0005634cellular_componentnucleus
X0005654cellular_componentnucleoplasm
X0005657cellular_componentreplication fork
X0005737cellular_componentcytoplasm
X0005813cellular_componentcentrosome
X0005856cellular_componentcytoskeleton
X0006281biological_processDNA repair
X0006310biological_processDNA recombination
X0006974biological_processDNA damage response
X0007098biological_processcentrosome cycle
X0010165biological_processresponse to X-ray
X0010332biological_processresponse to gamma radiation
X0022008biological_processneurogenesis
X0033063cellular_componentRad51B-Rad51C-Rad51D-XRCC2 complex
X0035264biological_processmulticellular organism growth
X0042148biological_processDNA strand invasion
X0043231cellular_componentintracellular membrane-bounded organelle
X0043524biological_processnegative regulation of neuron apoptotic process
X0050769biological_processpositive regulation of neurogenesis
X0051321biological_processmeiotic cell cycle
X0140664molecular_functionATP-dependent DNA damage sensor activity
X2000269biological_processregulation of fibroblast apoptotic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
XSER10

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CSER20

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PDB entries from 2024-11-06

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