8G04
Structure of signaling thrombopoietin-MPL receptor complex
Summary for 8G04
Entry DOI | 10.2210/pdb8g04/pdb |
EMDB information | 29644 |
Descriptor | Thrombopoietin, Thrombopoietin receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | tpo, tpor, cytokine, receptor, signaling, haematology |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 163776.40 |
Authors | Tsutsumi, N.,Jude, K.M.,Gati, C.,Garcia, K.C. (deposition date: 2023-01-31, release date: 2023-08-30, Last modification date: 2024-05-08) |
Primary citation | Tsutsumi, N.,Masoumi, Z.,James, S.C.,Tucker, J.A.,Winkelmann, H.,Grey, W.,Picton, L.K.,Moss, L.,Wilson, S.C.,Caveney, N.A.,Jude, K.M.,Gati, C.,Piehler, J.,Hitchcock, I.S.,Garcia, K.C. Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis. Cell, 186:4189-4203.e22, 2023 Cited by PubMed: 37633268DOI: 10.1016/j.cell.2023.07.037 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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